Soochow University Medical College Colloquium
Engineering Cell Function Through
Micro- and Nano- Structured Surfaces
by
Dr. Lance Kam
Columbia University, U.S.A
Dr. Kam earned his Ph.D. in Biomedical Engineering from Rensselaer Polytechnic Institute in 1999, and is an emerging leader in the field of creating complex biosurfaces at micrometer and nanometer scales. He is an Assistant Professor of Biomedical Engineering at
Abstract
Modern micro/nano-fabrication techniques promise the ability to capture the biological complexity required for organization of cells into functional tissues. This talk will introduce techniques for creating patterns and arrays of multiple biomolecular cues on engineered surfaces, including extracellular and cell-cell communication proteins, phospholipids (as a mimic of the cell outer membrane), and mechanically responsive structures. We have demonstrated new aspects of how cells integrate these signals, with the goal of driving cell function. Specific applications include neuron pathfinding, modulation of communication between cells of the immune system, and the role of protein mobility in cell response. The knowledge to be gained from these systems has wide implications in multiple fields of research, including basic cell biology, engineering, and medicine.
Date: 21 March 2008 (Friday)
Time: 3:00 pm – 4:00 pm
Venue: 712 Meeting Room
All are Welcome!
(科研办公室)
